If you arrive in Cozumel by ferry from Playa del Carmen, you’ll be in the city center. From there, you can walk across the iconic Benito Juarez square and take Quinta Avenida, which is 20 meters from the corner.
If you’re coming from the airport, you’ll find taxis available to take you to downtown Cozumel. You can ask the driver to take you to Quinta Avenida 121 in the downtown, and the journey takes 5 minutes.